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The chromatin modification patterns are often spread over thousands of base pairs.
In addition, the 3′ end modification patterns are represented in lower case (i.e., a and u).
Moreover, similar modification patterns are created upon simulating either a methyltransferase or acetyltransferase.
Changes in gene expression and histone modification patterns are often, but not always, associated with changes in DNA methylation.
The stochastic aspects of the establishment, maintenance, and decay of histone modification patterns are still largely unresolved.
Acetylation patterns of H4 histones suggested that these modification patterns are collectively maintained during mitosis and meiosis leading to long-term changes in gene expression.
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We further explored the underlying nucleosomal landscape across the three cell types to determine why our ChIP-chip histone modification patterns were not accounted for by nucleosome levels as shown in previous studies using ChIP-sequencing [19], [20], [22], [28].
The remaining effect modification patterns were not so clear.
However, PM10 effect modification patterns were somewhat different in Europe and the United States.
Similar histone modification patterns were observed in seedlings harboring individual Kan R or Kan S loci.
Surprisingly, these modification patterns were almost identical between expressed and unexpressed genes.
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