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Tobacco cessation should be encouraged, eventually by behavior modification or pharmacologic strategies (74).
A variety of proof-of-concept studies with murine sepsis models have demonstrated that this host response worsens disease outcome because its prevention through genetic modification or pharmacologic intervention improves survival.
Prediabetes is a stage earlier in the hyperglycemia/diabetes continuum where individuals are at increased risk of developing diabetes and where prevention efforts, including lifestyle modification or pharmacologic intervention, have been shown to be effective in preventing or delaying the onset of diabetes (1, 18).
Therefore, there has been growing interest in developing accurate ways of identifying individuals who have an increased risk of developing symptomatic AD so that they can be targeted for preventive interventions such as risk factor reduction, behavioral modification, or pharmacologic treatment.
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52 However, neither lifestyle modification nor pharmacologic therapy is effective in every patient.
Therefore, it is important to identify these individuals at high risk and to institute preventive therapy, be it lifestyle modification (3, 4) or pharmacologic therapy, to prevent the development of microvascular and macrovascular complications (5– 11).
Consequently, it was assumed that, by extension, raising HDL-C through lifestyle modification and pharmacologic intervention would reduce risk of CVD.
It begins with an interesting molecular biology or pharmacologic observation.
This technique induces a greater efficacy when it is associated with other non pharmacologic or pharmacologic options (level of recommendation I) [413].
Alterations in blood pressure may be related to other clinical events or pharmacologic interventions.
Patients were stressed using either maximal exercise on a bicycle or pharmacologic test with adenosine or dobutamine.
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