Sentence examples for modification of viruses from inspiring English sources

Genetic modification of viruses can confound the usual DNA sequencing methods used to identify the virus and make it even more difficult to track down the source.

Whereas genetic modification of viruses to evade the immune system is a daunting challenge and could yield hazardous variants, physical coating provides a simple "cover-all" that is not inherited by progeny viruses.

Building from recent achievements in the site-specific modification of virus for covalent surface tethering, we show in this work that stable 2D virus patterns can be generated in custom geometries over large area glass surfaces to yield templates of biological, biochemical, and inorganic materials in high density.

It has been shown that modification of virus capsids by PEGylation can significantly dampen the T-cell mediated immune response against the virus and stimulate the antibody response against a secreted antigen [26], [27], [30], [54].

Modification of membrane viruses with FSL constructs to create so-called kodevirions10 was achieved by contacting a suspension of virus particles with a buffer containing FSL-biotin and incubating at 37 °C for 30 60 min7.

The phenomenon of host specific restriction and modification of bacterial viruses stemmed from endonucleases within the cells that destroy foreign DNA molecules.

Additionally, the method allows the consecutiev modification of recombinant viruses without the need for additional selectable markers at each recombination step.

Another approach involves the use of genetic modification of dengue viruses to attenuate their virulence [ 218– 218].

These results provide some insight about the degree of T and B cell mediated immunity necessary for protection against Ebola virus and suggest that modification of the virus capsid can influence the type of immune response elicited by an Ad5-based vaccine.

In the spleen, Ad genome levels were affected more modestly by IR800 modification of the virus.

Incorporating an RhPV IRES element into alphavirus vectors offers an alternative solution that does not require the expression of fusion proteins or modification of the virus structural proteins.