Sentence examples for modification of tumour from inspiring English sources
Igf2-dependent developmental lethality and an Igf2-dependent modification of tumour formation occurred in p53 null mice.
The data suggest that modification of tumour response to CY by the addition of MISO varies from tumour to tumour, and is very dependent upon the MISO dose.
Owing to the modification of tumour cell surface antigens, the weak immunogenicity protected the tumour cells from host immune destruction, which hardly induced tumour-specific immune response.
These results indicate the likelihood of a seasonal factor (or factors) of importance for the regulation and modification of tumour cell proliferation.
Fully functional ETB receptors are clearly expressed on tumour vasculature and IRL 1620 shows promise for short-term modification of tumour blood flow.
Gene transfer to tumour cells offers new possibilities for cancer therapy based on the genetic modification of tumour cells (Marchisone et al, 2000).
The present study uses MCC and tumour xenografts, derived from established human colon carcinoma cell lines, to address the hypothesis that limited drug penetration in tumour xenografts can decrease chemotherapeutic cytotoxicity and that modification of the tumour environment by bortezomib might improve the penetration of anti-cancer drugs through tumour tissue.
Another protease important for the modification of the tumour microenvironment is procathepsin-L and its secretion is controlled by Rab4 [ 42].
Criteria for withdrawal from the study were as follows: intolerable side effects as judged by the investigator or the patient, patient decision to discontinue treatment for any reason, recurrent grade 3 or 4 drug-related toxicity despite dose modifications, progression of tumour and serious allergic reactions to any of the study drugs.
Our study links hTRM9L and tRNA modifications to inhibition of tumour growth via LIN9 and HIF1-α-dependent mechanisms.
Among MMPs, MMP-2 and MMP-9 play a critical role in the modification of ECM and tumour invasion.
