Sentence examples for modification of tumor from inspiring English sources

Trivedi, M., Talekar, M., Shah, P., Ouyang, Q. & Amiji, M. Modification of tumor cell exosome content by transfection with wt-p53 and microRNA-125b expressing plasmid DNA and its effect on macrophage polarization.

Core services include processing of hematopoietic stem cells for autologous or allogeneic transplantation, generation of tumor vaccines using genetic or culture mediated modification of tumor cells, and preparation of immune cell populations for adoptive cellular therapy.

Various methods for "xenogenization" (modification of tumor cells) were suggested: induction of new foreign antigens, treatment with either chemicals or enzymes and use of mutagens.

Moreover, expression and post-translational modification of tumor biomarker proteins, which ultimately play a key biological role in neoplastic cells, cannot be revealed by nucleic acid-based technologies.

Accordingly, identification of the physiological roles of nuclear Ptc-ICD7 fragments in the regulation of gene transcription and modification of tumor suppression should be future prospects.

The hypoxia-induced synthesis of HIF-1 α causes modification of tumor microenvironment.

This finding demonstrates that the modification of tumor-targeting moieties might be necessary to increase tumor gene expression specificity, and incorporating PEG could effectively reduce toxicity in RES organs after intravenous injection.

New-generation melanoma vaccines, which are based on genetic modifications of tumor cells to express cytokines, generated long-lasting systemic anti-tumor immunity in animal models.

Viral modifications of tumor cells were evaluated for their ability to induce a protective tumor response in model systems of rat fibrosarcoma, liver metastatic rat tumor cells, lymphoid tumor cells and hamster tumor cells.

In this study, we show that EN2 is indeed present in the membrane of cancer cells and that it is secreted through an active mechanism that is dependent on vesicle formation, and that cells that take up exogenous EN2 protein undergo distinct changes in behavior that could profoundly influence tumor development through modification of the tumor microenvironment.

The flexibility and specificity of nanoparticle-based delivery systems provide an opportunity for both targeting the immune system to initiate a potent immune response and targeting the tumor tissue for a local modification of the tumor microenvironment.