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The first one is about the modification of the function allocation by dividing functions or tasks between people and machines.
Then (as proved in [3]), Theorem 1.1 holds (once again, the LS condition amounts to proper ellipticity plus complementing condition and proper ellipticity is equivalent to ellipticity if and ) and it is straightforward to check that the proof of Theorem 1.2 carries over to this case if If so, Corollary 2.1 is also valid, with a similar proof and an obvious modification of the function spaces.
Proposed mechanisms include neuromodulatory effects on different enzymes and secondly on amino acids and the selective modification of the function of epileptic neurons [ 26 ].
Changes in the 3′ part of the microRNAs are widely the most found, most of the time they do not lead to a modification of the function of the microRNAs [ 12, 14].
Post-translational modification of the function of BCL-2 family of proteins, and in particular, the pro-apoptotic function of the Bad and Bim, both pro-apoptotic proteins, were also investigated by determining the phosphorylation of these proteins in conjunction with a variation in OS in GBM patients.
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Some progress has been made by examining proteins that participate in well-defined signaling pathways and addressing the effect of their modification on the function of the signaling network.
Equally, the effects of experimentally designed structural modifications on the function of channel variants in different human cell types, including residues putatively involved in post-translational regulation [ 34– 37], remain to be explored.
The discovery of the role played by epigenetic modifications on the function of paternal genome has prompted novel attention on the function of sperm DNA during embryo development.
Taking together the results from the literature summarized above and the present findings, it appears that withdrawal from acute or chronic PCP administration induces a negative affective state through modification of the functioning of numerous neurotransmitters and their related proteins in various cortical and subcortical brain regions.
Since modifications of the function of the main receptor form may have dramatic consequences on fitness and may not reach significant frequency in the general population, genetic variations in alternative exons that are expressed at low levels or only under specific conditions may lead to more subtle phenotypic differences that underlie the observed variation in OPRM1-dependent phenotypes.
Isoforms represent variants of a gene that can perform the same function, a different function altogether, or a slight modification of the same function (Little et al. 2010).
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