Sentence examples for modification of target from inspiring English sources
These methods are also instrumental for modification of target genes including gene truncations, site-specific mutagenesis and domain swapping.
The most common way to transmit these signals is by covalent modification of target proteins within the signaling pathway, most often adding a phosphate group (phosphorylation) or removing a phosphate group.
Being mobile, impurity atoms, vacancies and interstitials can recombine and/or precipitate in the form of stable complexes which leads to the modification of target material properties.
Firstly, a double strand DNA was designed with 5′-SH modification of probe DNA and 5′-OH mofificatargetf target DNA.
The history of transgenesis is marked by milestones such as the development of cellular transdifferentiation, recombinant DNA, genetic modification of target cells, and finally, the generation of simpler genetically modified organisms (e.g. bacteria and mice).
The subsequent covalent modification of target proteins and the associated changes in their function account for the physiological response.
For example, hydrophobic drugs can also be loaded into p-FE to obtain a theranostic nanoplatform and functional groups can be imparted at the terminal of PEG chains on p-FE for modification of targeting moieties to achieve molecular imaging of specific targets in vivo.
In the aftermath of his failed reform, Kosygin spent the rest of his life improving the economic administration through the modification of targets; he implemented various programmes to improve food security and ensure the future intensification of production.
Further modifications of target compounds are present at C-5 position of the pyrimidine ring.
FOXP3 is known to both activate and repress target genes by epigenetically regulating histone modifications of target promoters.
(4) Whether intra-nuclear localization, three-dimensional organization, or epigenetic modifications of target DNA element potentially affect the binding of engineered TALE and Cas9 gRNA warrants further investigations.
