Sentence examples for modification of synapses from inspiring English sources

The research raises the exciting possibility that thrombospondin may contribute to the modification of synapses thought to underlie learning and memory, points out Douglas Fields, a neuroscientist at the National Institutes of Health in Bethesda, Maryland.

It is widely believed that activity-dependent modification of synapses is the brain's primary mechanism for learning and memory.

Early childhood is a period of rapid and dynamic changes in the central nervous system, such as myelination, modification of synapses, and pruning.

Furthermore, the deterioration in performance and the differences noted in AD and DLB patients may be due to the different speed at which the process of the protein degradation occurs for functional modification of synapses.

Young children's brains undergo dynamic changes, such as myelination and modification of synapses, which can make their brains vulnerable to these glycemic excursions and potentially lead to neurocognitive deficits (12).

In contrast to long-term plasticity, short-term plasticity (STP) features the modification of synapse weight that can only last from tens of milliseconds to a few minutes and quickly recover to its initial state [66], as described in Fig. 9.

For example, specific transcriptional programs direct the neurotransmitter phenotypes of neuronal populations, the targeting of axonal projections, or the modification of synapse numbers in response to neuronal activity.

However, some data supports a role for both tau in neurofibrillary tangles, and Aβ surrounding plaques, as contributors to modifications of synapses in AD [ 16– 16].

Here we combined paired recording, computer simulation and biocytin-labelling to study functional organization and activity-dependent modification of glutamatergic synapses of SG EINs.

This agrees with developmental animal studies which show that early-life sensory experience leads to the strengthening and modification of existing synapses (rather than an increase in synaptogenesis), and can alter long-term somatosensory cortical topography and corpus callosal structure (Bourgeois et al. 1989; Fox 1992; Wang et al. 2007).

A prominent state of the hippocampal network is theta activity at 4 8 Hz in rat in vivo[18], which is associated with synaptic modifications of CA3-CA1 synapses in freely-moving rats[19].