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1) First, the motivation for each modification of stimulus parameters should be explained more clearly.
It would be nice to see what the model predicts for the ramped SFG. 1) First, the motivation for each modification of stimulus parameters should be explained more clearly.
All previous methods involving closed-loop or activity-guided optogenetic stimulation have used a physiological measurement to trigger static optical stimuli without corrective action or modification of stimulus parameters following stimulus onset (Leifer et al., 2011; Stirman et al., 2011; Paz et al., 2012; Krook-Magnuson et al., 2013; O'Connor et al., 2013; Siegle and Wilson, 2014).
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This is amplified by the modification of the stimulus material which did not contain any brand information.
Figure 6 summarizes the effect that modification of the stimulus conditions, as reported in this paper, has on our proposed model of SI activity.
Modification of ABR stimuli is discussed to improve wave V synchronization in ANSD patients.
The animals were then tested for 10 sessions on a selective attention task, similar to the preceding task but with modifications of the stimulus parameters and the addition of unpredictable olfactory distractors on one-third or the trials in each daily test session.
Despite the diuretic effect, the modification of the adrenergic stimulus pattern was not strong enough to clearly affect MAP or heart rate.
Reduced discrimination between response outcomes may interfere with adjusting responses to obtain the most favourable outcome both with regard to subsequent trials and longer term modification of the strength of stimulus-response mappings.
Interestingly, this region contains not only tyrosine phosphorylation site Y225, but also contains a typical conjugation site for the small ubiquitin-like modifier (SUMO), K223, or putative WW domain binding site, suggesting that post-translational modification of THOC5 by extracellular stimuli by cytokines/growth factors or heat shock may influence RNA-binding potency and/or selectivity of THOC5.
Projections from the prefrontal cortex to the amygdala mediate extinction, with complex circuitry involving the central nucleus, the basolateral complex, and the intercalated masses playing a role in the modification of responses to previously conditioned stimuli.
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