Sentence examples for modification of signalling from inspiring English sources

For example, covalent modification of signalling proteins allows for the accumulation of a signal over time.

Chaperones also participate in the post-translational modification of signalling molecules, the assembly and disassembly of transcriptional complexes and the modulation of immunogenic proteins (Bagatell, 2004).

Moreover, chemical modification of signalling proteins by ITCs may be complemented by modification of receptor proteins, as has previously been shown for the TRPA1 receptor [39], [40].

Aberrant O-GlcNAc modification of signaling proteins, metabolic enzymes, and transcriptional and epigenetic regulators has been implicated in cancer.

The unveiling point mutations within the kinase domain, gene amplification or overexpression, or modification of signaling pathway have been implicated in drug resistance.

Concerning the QLT0267-related 3-fold, unexpected increase in ILK activity in 3D UTScell culturestures, it can be speculated that such effects result from transcriptional and posttranscriptional modification of signaling pathways as well as from changes in protein-protein interactions induced by cell-matrix interactions in the 3D microenvironment.

None of the primary cultures or lung cancer cell lines revealed such a drastic modification of signaling as a function of transformation.

Previous works and ours suggest that the accumulation of esterified cholesterol may lead to a modification of signaling pathways associated with proliferation and migration in tumors.

Polyphenols influence mental health and cognition, namely, via energy metabolism and modification of signaling pathways and gene expression involved in the ability of a neuron to strengthen and change synaptic connections.

Modification of signaling cascades, such as highly conserved signaling pathways including insulin/Insulin-like growth factor 1 (IGF1), target of rapamycin (TOR) and sirtuin, for enhanced cellular responses to stress, is recognized as key to life span extension and accompanying reduced age-related pathology [ 3].

In this process, secondary modifications of signaling proteins may be crucial for the biological activity of these proteins.