Sentence examples for modification of reactive from inspiring English sources

The library of polymers with chemical diversity has been synthesized by (i) polymerization of functionalized monomers or (ii) post-polymerization modification of reactive polymers.

This redox shift to a more oxidative status during aging is thought to be responsible for oxidative modification of reactive protein cysteine (cys) residues that are involved in redox signaling upon oxidative stress (Cai and Yan 2013; Ying et al. 2007).

One conclusion of these studies, is that upon binding of CAPE to the integrase, nitrogen or sulfur nucleophiles may not be properly situated in the vicinity of the phenethyl aryl ring to allow reaction with and covalent modification of reactive functionality, such as isothiocyanate groups.

The mechanism was proposed to involve modification of reactive oxygen species (ROS /redox signaling.

Examination of proteins associated with eigenprotein #1 profile showed enrichment of proteins related to modification of reactive oxygen species.

In the presence of all NO and HNO donors tested, S-oxidation rather than S-nitrosylation was the dominant modification of reactive cysteine residues of GSTP1.

Oxidative modifications of reactive cysteines cause changes in protein structure and function; they affect localization and physical interactions, as well as the capability to undergo further posttranslational modifications (e.g., phosphorylation).

Both Nrf2 itself and KEAP1, which acts as a negative regulator of Nrf2 activity, are susceptible to oxidative thiol modifications of reactive cysteines which regulate their functions [27,30], and are therefore potential targets of NADPH oxidase-generated ROS.

Since cross-link formation is a reflection of dynamic collisions that result in chemical modifications of reactive residues [ 31], our finding of enhanced cross-linking between positions 175 and 311 in the presence of transport substrates suggests that conformational changes occur involving the proximal end of TMD8 in relation to TMD5 upon substrate binding.

In this review, the modification of representative reactive polymers for the delivery of different therapeutic payloads are summarized.

Post-polymerization modification of this reactive precursor was conducted by an initial substitution of VBC chloride with thiouronium (TU) followed by conversion of TU into thiolate via reaction with either KOH or NaBH4.