Sentence examples for modification of peptides from inspiring English sources

Morrison, P. M., Foley, P. J., Warriner, S. L. & Webb, M. E. Chemical generation and modification of peptides containing multiple dehydroalanines.

Thiol-X chemistry has proven to be a valuable toolbox for modification of peptides, proteins, monomers, and polymers.

Artificial synthesis and site-specific modification of peptides and proteins has evolved into an indispensable tool for protein engineers and chemical biologists.

The quest to enlarge the molecular space of functional biomolecules has led to the discovery of selective, mild and high-yielding chemical reactions for the modification of peptides and proteins.

(Unrelated to the posttranslational modification of peptides, we have also identified the egl nine homolog-also a prolyl hydroxylase).

The development of methods for the modification of peptides and proteins under benign aqueous conditions has received a great deal of attention from both industrial and academic laboratories.

Since no modifications of peptide structure was observed while wtEBO16 was able to induce PC vesicle aggregation and to promote vesicle leakage (data not shown), the endothermic behavior was correlated with these events, since modification of peptide structure was not observed.

The first modification of peptide with mass 1705.7642 Da is an N-terminal loss of NH3 with −17.0265 Da and cyclization of glutamine (Q) [17], while the second modification of peptide with mass 1721.7544 Da is an extra oxidation of methionine (M), which leads to an increase of the mass by 15.999 Da (net change 15.999 17.0265 ≈ −1 Da).

For the global proteomic dataset, carbamidomethylation of cysteine and iTRAQ 4-plex modification of peptide N-termini were set as fixed modifications, and oxidation of methionine and iTRAQ 4-plex modification of Lys were set as variable modifications.

The structure of the DiLeu isobaric labeling reagent follows that of other isobaric reagents in that it is composed of a reporter group, a balance group, and an amine-reactive group: an N, N-dimethylated leucine makes up the reporter and the balance groups, and a triazine ester amine-reactive moiety enables selective modification of peptide N-termini and lysine side chains.

Many structural modifications of peptides guided by rational design and molecular modeling have been established to develop novel synthetic approaches.