It is, however, not evident how the relatively minor morphological modification of part of that structure in the haplochromines [ 12] might function as an evolutionary key-innovation.
Another important finding of our studies is that interactions with the nucleobase and ribose can be additive, and thus the loss of binding energy from modification of part of the nucleoside can be compensated for by the gain of energy from modification of another part of the nucleoside.
Alternatively, they may solve the problem of vision at low light levels by modifications of parts of the visual system other than ocular morphology, e.g., at the level of the retina.
Thus, modularity is considered a key feature of biological organization that allows the modification of certain parts of organisms with minor effects on other parts, thereby contributing to evolvability [ 3].
Modification of right part based on the compound 16d which was disclosed in our previous communication led to the identification of compound 26i as a flagship compound.
However, in practice the actual data about the system may differ from those used in the simulation model (e. g., modification of the part mix).
Therefore, until recently the progress in the vehicle control systems has been related first of all to the implementation of more powerful and efficient hardware accompanied with cautious modification of software part.
As shown by several studies, the simple modification of a part of an interface can change information seeking and eye movement behaviors, as well as decision-making processes, and therefore can modulate how a task is performed (McCrickard et al., 2003; Rousseau et al., 2007).
Using the Bottle Material Volume Evaluation Tool the system calculates two factors to evaluate the material volume of each bottle part and compare it to the minimal one for the specific volume and to quantify the effect of the modification of the part's dimensions on the volume of the packaging material.
Most importantly, d-form analogs were metabolized much faster than their l-counterparts, thus clearly pointed out that compared to guanine, modification of glycosyl part might be a better choice for the development of L-guanosine analogs for the treatment of HIV.
