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The combined benefits of the molecular doping in terms of bulk, surface, and texture properties lead to an improvement in the photocatalytic activity for H2 generation with visible light, which underlines the importance of organic chemistry protocols for the chemical modification of newly developed metal-free, polymeric photocatalysts.

Likewise, the antiviral effects are related to increasing the lysosomal pH, which disrupts hydrolases and inhibit the post-translational modification of newly synthesized proteins [ 23].

Consistent with this hypothesis, in Schizosaccharomyces pombe, chromatin-modifying complexes travel with Pol ε to control modification of newly replicated chromatin at the fork (Li et al. 2011a).

SAM is of great importance during cell growth as it is needed, e.g., for the modification of newly synthesised DNA [ 8], linking sulphur metabolism to the growth phase [ 7].

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For example, the bacterial production of biologically active, complex multimeric proteins such as antibodies is limited by the absence of the enzymatic machinery involved in post-translational modification of newly-synthesised proteins [ 1, 2].

N-glycosylation is an important stage of posttranslational modifications of newly synthesized proteins performed in the ER lumen [ 109].

Synthesis of a unique modified glutamate residue called carboxyglutamate (Gla) results from post-translational modifications of newly synthesized inactive coagulation factors like Prothrombin in the liver endoplasmic reticulum by a vitamin K-dependent carboxylase [ 27].

The endoplasmic reticulum (ER) has two vital roles in the cell – it is a major intracellular calcium store and it enhances post-translational modifications of newly synthesized proteins destined for secretion, cell surface expression or organelle biogenesis.

In the joints with severe clinical arthritis, accumulation of cartilage was still apparent, while in joints with declining clinical symptoms, an increase in what was observed as mineralisation of cartilage and newly formed bone took place, in addition to modification of the newly formed bone by OCs.

One up-regulated protein of interest in the present study was Heterogeneous nuclear ribonucleoprotein H (HNRPH1), a member of Heterogeneous nuclear ribonucleoproteins (hnRNPs) which are complexes of RNA and protein present in the cell nucleus during gene transcription and subsequent post-transcriptional modification of the newly synthesized RNA (pre-mRNA).

Identifying additional mechanisms that allow for the reproduction of histone modifications within the chromatin of newly synthesized DNA will be important for understanding how gene expression programs are controlled.

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