Sentence examples for modification of key from inspiring English sources
Metabolic engineering involves the manipulation or modification of key genes in metabolic pathways to accomplish the goal of increasing the production of a substance of interest.
Antibody engineering enables modification of key properties (immunogenicity, valency, biological inertness, pharmacokinetics, clearance route, site-specific conjugation) in order to produce targeting agents optimized for molecular imaging.
Genetic modification of key factors involved in fatty acids metabolism revealed the influence of an active β-oxidation pathway on the extracellular degradation of PHA and subsequent HAs isolation.
A wide variety of potential liabilities in the lead candidate(s) may be exposed that require correction, including the propensity to aggregate, poor solubility, propensity to fragment, deamidation, oxidation, cyclization, or other chemical modification of key residues, disulfide bond shuffling, glycation, and so forth.
Firstly, many previous instances showed that chemical modification of key groups of enzyme was very important to the stability of enzyme [32].
For a long time, chemical modification of key groups has enabled enzyme improvement in terms of stability and other features [8 10].
This finding potentially provides a new means of targeted metabolic engineering of metabolites in seeds, such as oils and flavonoids, through post-translational modifications of key transcription factors, such as TTG1, which specifically affects desirable seed characters while maintaining their normal functions in regulating other plant traits.
It also remains possible that NMD efficiency could be regulated by intra- and extracellular cues, perhaps through posttranscriptional modifications of key NMD factors.
The spatiotemporal dynamics of DNA repair and checkpoint proteins that cooperate in large complexes to survey genome integrity in eukaryotic cells suggests that one of the roles of the checkpoint response is to reorganize the protein composition of such complexes through the posttranslational modifications of key components with the aim of rapidly reacting to DNA damage [42].
Post translational modifications of key nitrogen control enzymes also occurs in response to nitrogen limitation.
Plant breeding is a process of human selection, which results in more desirable traits due to genetic modifications of key genes controlling plant development [ 1, 2].
