Sentence examples for modification of importance from inspiring English sources

Proteolytic processing of proteins is an irreversible post-translational modification of importance for a wide-variety of biological processes, including cell division, cell death, cell differentiation, innate immunity, host-pathogen interactions, and intracellular protein sorting and trafficking.

A post-translational modification of importance in rheumatoid arthritis (RA) is the conversion of peptidylarginine to peptidylcitrulline by peptidyl arginine deiminase (PAD) [ 3, 4].

Protein arginylation and arginine methylation are two posttranslational modifications of emerging importance that involve Arg residues and their modifications.

N-Methylations of both DNA and histones are chromatin modifications of central importance in (epi genetics.

On the other hand, modifications of the importance score definition, or using different measures other than Gini impurity in building trees might improve performance.

For example, after years of describing static chromatin modifications, we are beginning to gain a glimpse into the dynamics of nucleosome assembly and modification, the importance of chromatin remodelers, histone chaperones and transcriptional elongation complexes, and clarification of their roles in development and disease.

If the modifications on Bim were of importance for apoptosis, downstream mitochondrial apoptotic effects should occur after these modifications, and the effects should be enhanced by the kinase inhibitor PD98059.

Considering that modification of the epigenetic profile of neuronal DNA provides a mechanism for activity-dependent epigenetic regulation in the adult nervous system, epigenetic modifications could also be of importance as modulators of individual response to antidepressant treatment.

In order to determine if the modifications of BimEL were of importance for the distribution of this protein between cytosol and mitochondria, cytosolic and mitochondrial cellular fractions were analysed by Western blotting.

For example, in Drosophila, post-translational O-GlcNAc modification was shown to be of importance for the regulation of Polycomb gene expression, while in vertebrates tubulin was even shown to contain sialyloligosaccharides [11], [28], [29].

We elucidated possible effect modification and thresholds for variables of importance for the association between parity and ovarian hormones.