Sentence examples for modification of hepatic from inspiring English sources

To investigate whether the modulation of local cellular cross-talks and the modification of hepatic adipocytokine expression could mechanistically explain the improvement of liver histopathology after laparoscopic sleeve gastrectomy (LSG) in adolescents with nonalcoholic fatty liver disease (NAFLD).

In this review, various systemic reactions associated with immune stimulation will be addressed, including: APR, hypersensitivity, induction or worsening of autoimmune diseases, modification of hepatic metabolism and vascular leak syndrome (VLS), with an emphasis on the mechanism involved.

The degree of oxidative modification of hepatic and primary tumor tissue proteins was assessed as previously described [14] through assessment of the levels of protein carbonylation and of protein sulfhydryl groups.

Substantial modification of hepatic DNA occurred and persisted for a period of 2-4 weeks after a single exposure to BaP.

The proposed mechanisms that were hypothesized by the authors included a role of the plant in carbohydrate intestinal absorption and/or modification of hepatic metabolic processes, since no effect was observed on plasma insulin [ 14].

The level of chemical modification of hepatic DNA in juvenile flounder was 2-4 folowerwer than that for juvenile sole and concentration of BaP 7,8-diol glucuronide in bile of sole was significantly higher than that in flounder bile, although the rate of formation of BaP 7,8-diol by hepatic microsomes was comparable for both species.

The modification of the hepatic fatty acid composition also changes the expression of genes considered as metabolic targets regulated by PUFA in the liver.

In parallel, there has been increasing recognition that the vasculoprotective effects of statins might reside not only in lipid modification but also in direct effects on inflammation manifested presumably through direct effects on the vascular lesion, or via secondary modification of the hepatic acute-phase response and constituent moieties, particularly CRP.

36 There were few adverse effects and there was no clinical modification on hepatic parameters.

Alterations of CRP levels and of serum PON1 activity could reflect modifications of their hepatic synthesis.

47 Animal studies on the aging liver have shown modifications of the hepatic physiology which affect drug metabolism.