Sentence examples for modification of heparan from inspiring English sources

The majority of remaining alleles affected genes that are involved in the modification of heparan sulfate.

We have previously demonstrated that Epac increases melanoma cell migration by modification of heparan sulfate [ 17].

The FGF signalling pathways participate in heparin sulfate (HS) modification of heparan sulfate proteoglycans (HSPGs) [ 30, 31].

Previously, we have reported that Epac increases melanoma cell migration by modification of heparan sulfate, a major component of the extracellular matrix [ 17].

Because different HS modification patterns are crucial for FGFR signaling and function (Guimond and Turnbull 1999), all the genes involved in the biosynthesis and modification of heparan sulfates as well as the other genes are candidates to be mutated in still elusive cases of Kallmann syndrome and IHH.

The modifications of heparan sulfate proteoglycans also comprise, besides the ones connected with the biosynthesis of the glycan chain, the ones concerning the transformation of the HSPG core protein [ 30].

Although we do not observe any asymmetry in Dally-like expression (not shown), differences in the distribution of Dally or the post-translational modification of either heparan sulfate proteoglycan (HSPG) might be present.

This peptide caused little or no change to the binding of heparan sulfate.

Heparan sulfate modification of proteins is essential for mouse development.

Sweet cues: How heparan sulfate modification of fibronectin enables growth factor guided migration of embryonic cells.

The transfusion of heparan sulphate would not influence our conclusions even if no exogenous heparan sulphate was cleared from plasma.