Sentence examples for modification of germ from inspiring English sources

"As a form of genetic modification of germ cells [eggs and sperm], MRT raises concerns about interference with nature, 'playing God', eugenics, and the potential impact on persons with disabilities," the NAS report says.

Methods for direct genetic modification of germ cells and zygotes have been utilised to generate genetically modified rats without using ES cells (Smits et al., 2006; Geurts et al., 2009; Izsvák et al., 2010).

"If a similar strategy proves successful in human pluripotent stem cells, then the options for reproductive biology, but also genetic modification of the germ line, are profound," Daley says.

These difficulties in the theory resulted in a variety of criticisms that were eventually to lead to the downfall of preexistence theory in its original form, although the theory was to have a long subsequent history through a modification of the "germ" theory (Detlefsen 2006 in Smith 2006; Roger 1997a, chp. 7; Roe, 1981).

Our study represents a novel characterisation of the dynamics of DNA modification of fetal germ cells in the male rat during the latter half of gestation.

Remarkably, alternative rearrangement patterns in Paramecium and other ciliates can be inherited maternally across sexual generations, with no modification of the germ line genome (reviewed in [ 48]).

One of the most intriguing topics in the field of epigenetic modifications of the germ line is represented by the influence played by the paternal diet on gametogenesis.

It is likely that epigenetic processes including changes in histone modifications affect the development of germ cell tumours.

The increasing number of genes affected by parental origin-dependent epigenetic regulation emphasizes the relevance of germ line-specific epigenetic modifications.

Imprinted genes should possess specific features in their DNA sequence that are responsible for establishment or maintenance of germ line-specific epigenetic modifications.

The mammalian genome undergoes major reprogramming of modification patterns in germ cells and in the early embryo.