Sentence examples for modification of doses from inspiring English sources

Since the pivotal PREEMPT studies, a variety of injection techniques have been proposed, with modification of doses or sites of injections.

Additional calculations were performed using the feature in OLINDA/EXM that allows modification of doses on body mass ratios to adjust the calculations to be more appropriate for the subject's individual body size.

Moreover, because of the emergence of bacterial resistance to antimicrobial agents as a result of their extensive use in animal husbandry, measures such as modification of doses of antimicrobial agents, control of Salmonella infections in primary production facilities, and effective epidemiologic surveillance must be implemented to determine potential routes and spread of infection.

Four major approaches are currently being explored in preclinical models, some also in patients: combination with agents that modulate cellular response and disposition of oxazaphosphorines; antisense oligonucleotides directed against specific target genes; introduction of an activating gene (CYP3A4) into tumor tissue; and modification of dosing regimens.

The authors concluded that CVVHF had little effect on micafungin kinetics, and no dose adjustment or modification of dosing interval was needed during CVVHF.

The implications of these findings for modification of dose-specific breast cancer risk by fractionation and protraction of dose are unclear, and the results could reflect effects of yet unrecognized confounding factors [ 45].

Third dose monitoring is commonly used, but this does not allow early modification of dose or time interval if high concentrations are detected, particularly in those babies given once daily aminoglycosides who might have only a short 48 hour course of treatment before negative cultures are confirmed.

Modifications of doses and dosing schedules were as follows: If the neutrophil count was ≥1.5 × 10/μl and the platelet count was ≥100 × 10/μl, we would begin the next cycle for both AC and SD.

Modification of the doses or the dose interval of D/F was made for haematologic toxicity based on the platelet and leukocyte count on the day of the planned treatment.

All patients were maintained on their baseline medications without modifications of dose through the course of this investigation.

Modifications of dose and/or frequency of administration of canakinumab were performed according to the judgment of the physician in charge based on the clinical picture and/or laboratory parameters.