(See above Rearrangement and modification of DNA).
Chemical modification of DNA can lead to mutations in the genetic material.
This is a seductive but rather slippery word that has come to mean a variety of things in relation to how molecular structures close to DNA work, in particular modification of DNA bases by methylation.
Some evidence implicates chemical modification of DNA.
No covalent modification of DNA or GNP surface is needed.
No sophisticated experimental techniques or chemical modification of DNA is required.
Blasco suspects that cloning can lead to chemical modification of DNA, possibly blocking telomerase from its target.
The biological results were eventually linked to an enzyme-specific modification of DNA by type I R/M enzymes.
DNA methylation is a covalent chemical modification of DNA catalyzed by DNA methyltransferases (DNMTs) and plays a crucial role in epigenetic modifications.
Here, a lethal lesion is defined as the local modification of DNA generated from the direct and indirect action of ionisation radiation (i.e. a double-strand break).
However, owing to their high activity, they can cause various cell and tissue disorders as well as destruction or modification of DNA structure [3].
