Sentence examples for modification of distinct from inspiring English sources

Oxidative burst of zymosan-stimulated granulocytes led to CML modification of extracellular proteins within 60 120 min. Predifferentiated MM6 cells, exerting NADPH oxidase activity but lacking myeloperoxidase activity, showed CML modification of distinct intracellular proteins within 1 3 days upon stimulation.

Collectively, our data reveal that during Listeria infection ISG15 modification of distinct ER and Golgi proteins increases secretion of cytokines which are known to counteract infection in vivo.

The aim of the present work was to investigate the age-related modifications of distinct human dermal fibroblast populations and their possible implication in skin aging.

The occurrence of similar or identical gene products in different spots is a common feature observed in 2-DE analysis and can be caused by post-translationally modifications of distinct amino acids of one single gene product [ 31].

Thus, by employing paired 'nickases' that recognize sequences separated by 4 to 20 base pairs (Fig.  2B), Ran et al. were able to achieve efficient (>40%) modification of three distinct genetic loci with a 200 1500-fold increase in specificity (66).

The inability of polyclonal antibody NMT-4 to detect nmt55/p54nrb in some ER+ tumors may be attributed to proteolysis during nuclear extraction and analyses or biochemical modification of functionally distinct isoform.

The neighboring chromatin environment and the genomic localization of modifications to distinct regions may give more valuable information toward gauging relevance and function.

Top-down proteomic studies from the laboratories of Freitas and Kelleher have also provided extensive information concerning the complexity and large number of distinct modification patterns that can occur on histones, but these methods do not address the substrate specificities inherent to individual enzymes and do not explicitly define the stepwise progression that connects two states (53, 54).

Experimental results presented in detail the surface modifications in the form of distinct changes in the static water contact angle across a range from 44.3 to 81.2 when compared to pristine PMMA surfaces.

Post-translation histone modifications and the various combinations thereof have been proposed to "write" the "histone code" creating extensive diversity through such combinatorial sets of modifications for the recruitment of distinct regulatory proteins and complexes [24].

The theoretical basis of PACT is thus preserved, while a number of distinct modifications to content and the mode of delivery were developed in the light of contextual factors described below.