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Furthermore, under this paradigm, the patient becomes an integral part of the healthcare delivery ecosystem, taking an active role in the identification and modification of disease related risk factors, while also assuming responsibility for critical aspects of their ongoing care (moving from being a passive consumer of clinical care to an active member of the overall healthcare team).
Formal implication of PRV in HSMI will require isolation in cell culture and fulfillment of Koch's postulates, or prevention or modification of disease through use of specific drugs or vaccines.
This also allowed for exploration of whether the early life environmental influences exerted their effect through modification of disease phenotype.
Each has demonstrated efficacy in terms of disease activity and symptom control, health-related quality of life and function and modification of disease progression.
Nevertheless, accurate evaluation of the benefit risk balance of treatments aimed at prophylaxis and/or modification of disease progression will remain a burden by using empirical protocols, even when longitudinal follow-up is well designed and outcomes strictly defined.
5, 6 Newer classes of medical treatments for T2DM are promising for modification of disease progression, but they are expensive and there is little experience with use of these agents over the long term.
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In addition, only two studies verified associations between modifications of disease markers and HS and both did not include exacerbation rate as a predictor over time [ 7, 11].
That NMD functions as a quality control mechanism tentatively suggested involvement of this particular RNA surveillance process in both the initiation and progression of neurodegenerative diseases and in treatment-induced modifications of disease symptoms.
Similar modification of metastatic disease by bevacizumab has been observed in animal models and selected human cases.
However, we speculate that the delayed start of treatment prevented a treatment induced modification of the disease's course.
As a surrogate for measuring renal function in the subjects, we estimated the GFR using a simplified form of the Modification of Renal Disease (MDRD) equation [ 13].
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changes of disease
modification of distance
modification of intensity
modification of congestion
modification of playstyle
modification of seizure
modification of tomato
modification of administration
modification of carbohydrate
modification of cell
modification of influenza
modulation of disease
modification of tumour
modifier of disease
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