Sentence examples for modification of canonical from inspiring English sources

Modification of canonical CTD by phosphorylation at specific serine residues is required for orchestrating transcriptional activities in better studied eukaryotes.

This study also shows that treatment-induced modification of canonical Wnt signaling activity changes the radio-sensitivity of ISPCs.

However, no consensus has emerged regarding a chemical mechanism for the damage of cellular DNA by 4. In the work described here, we explored the novel possibility that the mutagenic properties of the clinically used drug 4 arise via the drug's ability to covalently capture endogenous abasic (Ap) lesions in genomic DNA rather than by modification of canonical DNA bases.

Our results reveal the conserved meiotic toolkit in six diatom species and indicate that Stramenopiles share major modifications of canonical meiosis processes ancestral to eukaryotes, with important divergences in each Kingdom.

Chemically induced mutagenesis typically involves covalent modification of the canonical nucleobases of the DNA in target cells.

The inhibition of protein synthesis that occurs during cell stress is achieved by modification of the canonical protein synthesis machinery (eukaryotic initiation factors) and cells have therefore developed specialized mechanisms to bring about the recruitment of selective subsets of mRNAs to actively translate ribosomes under these conditions.

Four of the five amino acid variant positions within H2BE are located near post-translational modification (PTM) sites of canonical H2B, raising the question of whether PTMs may differ between the two proteins.

In addition to modifications of the canonical core histones, nucleosomes can also contain histone variants contributing to the nucleosome property (Talbert and Henikoff 2010).> In mammalian cells as in many eukaryotic cells from many different kingdoms the DNA can be methylated.

ATP-dependent remodelling complexes, histone post-translational modifications and replacement of canonical with variant histones can later modify nucleosomes, thus altering the function of specific chromatin regions [2] [4].

rCCA is a modification of the classical canonical correlation method that permits analysis of a small number of observations and a large number of variables in both sets.

H2BE's post-translational modifications (PTMs) differ from those of canonical H2B.