Sentence examples for modification of bases from inspiring English sources

Through DNA replication or error-prone repair events, the modification of bases can result in the alteration of genetic information because an oxidized base can form stable hydrogen bonds with multiple partners.

However, in vivo chemical modification of bases can expand this alphabet markedly, giving rise to a host of important biological phenomena.

DNA-damaging agents induce various types of DNA damage including modification of bases, intrastrand crosslinks, interstrand crosslinks (ICL), DNA protein crosslinks, single-strand breaks (SSBs), and DSBs.

In addition to having proper codon anticodon base pairing, there are a number of cases in which tRNA decoding requires the specific modification of bases in the anticodon loop.

Modification of bases by addition of a methyl group can physically inhibit binding of transcription factors and also permit recruitment of the methyl-CpG-binding domain proteins to promote regions, which can repress transcription initiation [ 42].

Consequently, the joint modification of base asphalt with RHA and BO could obtain desirable high temperature, low temperature and anti-fatigue performance.

For example, the hydroxyl radical causes lipid peroxidation, modification of DNA bases or protein damage and in turn, leads to tissue damage, chronic diseases and ageing [ 3].

Although all the four DNA bases can be modified by ROS, mutations mainly involve modification of GC base pairs, while AT base pair mutations are rarely observed [ 35].

This is a seductive but rather slippery word that has come to mean a variety of things in relation to how molecular structures close to DNA work, in particular modification of DNA bases by methylation.

Fluorescent moieties (Cy3) were incorporated into the ssDNA by chemical modification of guanine bases.

Oxidative stress in nuclei is known to induce either oxidative modification of DNA bases or single/double-strand breaks, which may lead to carcinogenesis.