Using the interpolations shown in Figure 3 c,d), we can then see how modification of a baseline parameter moves us away from the point at which both strategies are equivalent.
We then tested (using the same adjustments) for effect modification of sex, ethnicity, baseline glucose tolerance status (normal fasting glucose [NFG] vs. IFG), and insulin resistance (HOMA-IR < vs. ≥ median split) on the association of adiponectin with incident diabetes.
For primary endpoints, we checked for effect modification by baseline values of CD4 cell count, BMI, and baseline ART use status (HAART naïve, on treatment for less or equal to 3 months, or on treatment for 3 to 6 months).
For example, a modification of the acceptable range of baseline values can change the variance of the difference value after treatment minus baseline [ 6].
However, neither time until dose adjustment nor strategy of dosing modification was related to recovery of baseline renal function at the EOT (data not shown).
We next investigated effect modification by baseline participant characteristics.
To identify possible effect modification by baseline sleep and physical activity, the sample was stratified by indicators defined for both of these variables.
Objectives: Evaluate the relation between the modification of AT levels from baseline and circuit survival during CCRT.
Our method, which we have called HHTMass, consists of using the Hilbert Huang transformation for denoising followed by modification of the spectrum by baseline subtraction and rescaling.
The modification of treatment effect by baseline AHI was not explained by differences between patients with moderate compared with severe sleep apnoea in any of the adiposity measurements at baseline, age, or weight loss achieved at week 9 (−19.2 v −18.2 kg, P=0.55) between.
Compared with baseline, Modification of Diet in Renal Disease estimated glomerular filtration rates at the end of treatment were normal, with minor changes of −0.58, −0.84, and 1.45 ml/min per 1.73 m in the respective placebo and 10- and 20-mg dapagliflozin groups.
