Sentence examples for modification of alternative from inspiring English sources

However, basal resistance to TMV in N. benthamiana was not affected by modification of alternative respiratory capacity.

Modification of alternative splicing is known to be important in cancer development (12) and the epithelial-mesenchymal transition (13), and recent work has shown that somatic mutations affecting splicing can act as driver mutations in tumors (14).

In contrast to the situation in thymocytes, PS-1145 sensitized MEF to TNF, in line with a prosurvival effect of NF- κB-regulated genes, and/or, modification of alternative direct targets by IKK in these cells.

The functional studies of the common CCND1 polymorphism P242P showed a modification of the alternative splicing events in exon 4 because the G-to-A substitution alters the consensus sequence of the splicing donor site (Betticher et al. 1995; Howe and Lynas 2001).

Forced by the Lib Dems to hold a referendum on an uninspiring modification of FPTP called "alternative vote" as a coalition dowry, nearly all Tories campaigned for a "No".

Among the newly detected versions in this study we found several conserved gene neighborhood associations for AlbC-like CDPSs that might be indicative of alternative modifications and synthetic mechanisms for the dipeptides generated by them.

Here, we explore this subject on a genome-wide scale, describing the extent of association of histone modification with alternative splicing in two distinct mammalian cell types.

In addition, this platform for adenoviral modification allows for facile introduction of alternative targeting ligands.

Besides direct inhibition or modification of TLR signalling, induction of alternative regulative or antagonistic endogenous signalling cascades is another strategy in immune evasion.

Although this modification is the rarest type of alternative splicing found in normal cells, exonization events in cancer cells are frequent and may be associated with impairments in splicing regulatory factors [ 61].

To evaluate the extent to which a population evolves to such a barrier, stochastic computer simulations were performed on clonal populations in which the genome-wide deleterious mutation rate was subject to modification through an unbounded range of alternative states, with the mutation rates (U) of adjacent allelic classes differing by a constant factor, 1 + λ.