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Asparagine-linked (N-linked) protein glycosylation is one of the most abundant types of posttranslational modification, occurring in all domains of life.
The scanning electron microscopy (SEM) surface and cross-sectional micrographs reveal that surface topography is an indicator of the degree of modification occurring in the nitrided layer.
A reduction in the NAA/creatine ratio was also found at the thalamic level in patients affected by trigeminal neuropathic pain when compared with other non-neuropathic trigeminal painful syndromes, as a sign of the structural modification occurring in the course of central sensitization processing [8].
In fact, the NAA levels were within the normal ranges even in those patients experiencing frequent tension-type headache episodes, suggesting that the neuronal structural modification occurring in the course of central sensitization processing [8] would not be a relevant phenomenon for NAA serum reduction.
In conclusion, Raman COIN technology is emerging as a powerful tool that will be useful for multi-parameter simultaneous measurements of protein and protein modification occurring in a single cell.
Glycosylation is the most widespread post-translational modification, occurring in over 50% of all cellular proteins.
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FTIR analysis was carried out to assess the areca nut extract sample and respective chemical modification occurred in modified dyed sample.
For H substitutions the only modification occurs in C-Br o C-Cl distances, that increase 60%% for C-Cl bond and 75%% for C-Br.
Our findings suggest that CML modification occurs in vivo and in vitro when oxidative stress from e.g. inflammatory cells is present, indicating that CML may represent a marker for oxidative stress.
With the irradiation by femtosecond (fs) laser with high repetition rate, GeS2 micro/nano-crystalline formation and microstructural modification occurred in pseudo-binary GeS2 In2S3 glass, while almost no similar change was observed in GeS2 glass.
This striking ceramide modification occurred in 85.7% of the pancreas tumors so far investigated.
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