Sentence examples for modification may serve from inspiring English sources
Moreover, DNA methylation and histone modification may serve as good epigenetic indicators of chromatin states, such as gene activation (H3K4me3 and H3K36me3) and repression (H3K9me3 and H3K27me3).
This dynamic modification may serve to physiologically down regulate eNOS by NO under normal conditions [46].
It has been speculated that the post-transcriptional rRNA modification may serve to increase the stability of the local RNA structure or decrease risk of degradation [4], [13].
We chose not to exclude ions based on differences of charge or modification, as this would have increased the exclusion list beyond a practical size, and additionally we reasoned that some redundancy based on differences of charge or modification may serve to increase the confidence of identification.
This modification may serve more than one function because longer HTT polypeptides, both wild-type (WT) and mutant, are SUMO modified downstream of exon 1. SUMO-2 overexpression causes mutant HTT to accumulate in cells.
Alternatively, NET histone modifications may serve non-traditional purposes.
Such modifications may serve to expose a more complete range of candidate TFs involved in mtDNA transcription regulation.
Epigenetic changes including DNA and histone modifications may serve as a switch of reciprocal regulations between miRNAs and lncRNAs.
These histone modifications may serve as a binding platform for non-histone proteins, whose activities change chromatin structure and function.
Abundance differences in protein isoforms, degradation fragments, or post-translational modifications may serve as biomarkers for early detection of breast cancer, but it is impossible to discern one protein species from another when proteins are digested before separation.
Given that our proposed method is based on a multiple-motif model, we believe it can be applied to other TFs, with some modifications, and may serve as a basic tool to discover important cis-regulatory features.
