Obviously, if one forces two dependent ES descriptors to be combined in a single equation, the signs in the regression coefficients of key structural modifications may change, and thus fail to point out the real tendency of impact to ligand binding in an analog set.
First, such modifications may change the result of protein domain search like InterProScan that are handled in different places (e.g. Chado, GBrowse MySQL, GreenPhylDB).
Where a modification is considered to be moderate, Coons et al. [ 7] suggest that the modification may result in changes to the (perceived) meaning of the assessment items.
Formation of the age-specific, CKm immunoreactive 130 kDa protein suggests that oxidative modification may cause structural changes that lead to aggregation.
Even tiny differences in the styles or structures of ligands modification may lead to apparent changes in Si QDs PL.
The observed responses to bladderwrack consumption in this study suggest that dietary modification may lead to significant changes in the regulation of the menstrual cycle by increasing the length of the cycle, stimulating ovulation, and lowering the estrogen/progesterone ratio in pre-menopausal women.
Work modifications may include changes to the workplace, equipment, work design and organisation, working conditions and/or work environment [ 5].
Moreover, post-translational modifications may induce changes in Rad9-binding mode and allow it to interact with other partners (Du et al, 2006; Hammet et al, 2007).
More complex behavioral changes for lifestyle modification may be dependent on additional variables, such as the perception of self-efficacy, that were not explored in this study.
Therefore, change of surface charge by carboxyl modification may affect silica nanoparticles' cellular uptake.
