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The modification may be caused by oxidants released by neutrophils at the site of inflammation [37], or truncation by endogenous proteases from neutrophils [17], mast cells [18], and cytotoxic T cells [38] or exogenous proteases originating from the house dust mites Dermatophagoides pteronyssinus [39] and Dermatophagoides farinae [40].
We cannot exclude a possibility that the apparent effect modification may be caused by gene(s) in proximity to the HFE gene in chromosome 6 that influence or regulate PP or resulted from effects of less-common HFE variants, such as S65C (Pedersen and Milman 2009).
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Aberrant histone modifications may be caused by improper activities of histone-modifying enzymes, leading to inappropriate expression of tumorigenesis-related genes [ 5, 6].
27 Lack of significant modification of flow velocities in the CRA may be caused both by no change in IOP (and perfusion pressure) after adding dorzolamide and by low baseline IOP.
The greater biodegradation efficiency of the fungal strain in comparison to M. populi VP2 may be caused by a modification of the A. sydowii VP4 cell surface that increases cell permeability to hydrophobic compounds and thus enhances the extent of pollutants degradation.
In addition, Lemmon et al. [ 24] suggested that gene expression may be caused by the modification of cis regulatory elements.
Fractures and disruptions were also observed in other lignin-rich regions including cell corners and compound middle lamellae, suggesting that the structural changes may be caused by lignin modification and/or removal.
Homosexuality may be caused by chemical modifications to DNA.
The further analysis of the details of the numerical result suggests that the chemical effect of carbon monoxide addition may be caused by the modifications to the flame temperature, soot surface growth and oxidation reactions.
The reduction of specific force may be caused by posttranslational modifications of contractile proteins induced by ROS.
Finally, Olson and Solomonow[ 15] studied the effect of repeated cyclic lumbar flexion and concluded that modifications in the EMG patterns along cycles may be caused by increasing muscular fatigue.
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