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Therefore, change of surface charge by carboxyl modification may affect silica nanoparticles' cellular uptake.
For each macro-group, several representative examples are discussed and critically evaluated in order to provide the reader with keys to the understanding of how the different catalytic systems act and how their modification may affect their performance in terms of activity and selectivity.
Our observation that SUMOylated VHL localizes to the nucleus, while ubiquitylated VHL is cytoplasmic, suggests that posttranslational modification may affect VHL subcellular localization and its inhibitory function on HIFα.
The fact that histone modification may affect gene transcription has been recognized for many years.
Histones modification may affect the expression of patterning genes during morphogenesis [ 29].
A drawback of this method is that the small structural modification may affect the somatostatin receptor binding affinity [ 52].
Similar(49)
It is shown how some clay features such as the clay organo-modification may affect the polymer behavior.
Finally, a range of posttranslational modifications may affect function.
Posttranslational modifications may affect the activity of the estrogen receptor.
How epigenetic modifications may affect the development of these disorders should, however, be examined in further studies.
The epigenetic mechanisms established by histone modifications may affect the transcriptional silencing of HIV-1 and viral latency.
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