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For these latter applications, surface modification is usually necessary to improve wettability, printability and adhesive properties.
The property modification is usually brought about by a change in the microscopic structure of the material.
However, multi-step post-synthesis surface modification is usually required to functionalize as-made NCPs before their biomedical applications.
ASIP Meister supports a flexible pipeline model where fetch or decode stages are changed with execution stages whose modification is usually supported by architecture description languages (ADLs).
This modification is usually catalysed by damage activated ATM kinase and further transactivates the kinase inhibitor p21, leading to cell-cycle arrest at the G1/S checkpoint.
A number of chromatin-modifying enzymes are sumoylated, and the modification is usually linked to repression (Garcia-Dominguez and Reyes 2009).
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However, the organic matters which were used in chemical modification are usually expensive and harmful.
It is therefore often necessary to use eukaryotic expression systems to produce correctly processed proteins, but even then the pattern of modifications is usually different from the natural situation.
These modifications are usually the result of workers' activities such as food accumulation and nest construction.
In some older plants, the placement of new shells or topology changes in HENs can be expensive due to various reasons and only minimum topology modifications are usually allowed.
Considering the costs of design modifications are usually very expensive and it may make the product (system) more complex, a novel idea is proposed, which to generate a user manual by analyzing the interaction between product behavior and user behavior during the early design stage to help designer to minimize the possibility of design modification after prototyping phase.
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