Sentence examples for modification is unknown from inspiring English sources

Whether the two bands retained in the extract correspond to different isoforms or to post translational modification is unknown.

The exact mechanism of eNOS modification is unknown but in vivo experiments have shown that eNOS activation in aortas and iNOS transgenetic expression in mouse heart both result in NO-induced protein S-glutathionylation [45].

Which kinase performs this modification is unknown, but ERK2 and protein kinase D were previously excluded [ 44, 54].

The methylation of arginine residues has been shown to take place in other pre-mRNA splicing proteins though the role of this modification is unknown [ 38].

Currently, there are no methods that are reliably able to determine if an organism has been genetically altered if the nature of the modification is unknown.

Another inositol 3′-phosphatase, myotubularin-related protein 4, localizes to endosomes and is also poly-ubiquitinated by NEDD4, although the role of this post-translational modification is unknown (Plant et al., 2009).

However, the knowledge and attitudes (of men at increased risk of PC) towards dietary modification are unknown as is their willingness to adopt such advice.

Several phosphorylation sites have been reported for all members in the KDM3 subfamily that could be important for substrate recognition and signaling, but the impact of these modifications is unknown at present [ 19, 111].

Whether this is due to failure of AsO2 to recognize the 22-kDa α- and 15-kDa β-zein promoters or the silencing of these genes through epigenetic modifications is unknown at this time.

However, the 5hydroximethylcytosine (5hmC) is formed by enzymatic oxidation over the 5methylcytosine catalyzed by a family of iron-dependent dioxygenases, recently identified in neurons., The functional significance of these oxidative modifications is unknown; however, they have been involved in the dynamics of DNA methylation.

Fj is able to phosphorylate both Ft and Ds (Ishikawa et al., 2008) and modify the binding affinities between the two proteins in vitro (Brittle et al., 2010; Simon et al., 2010); however, the functional in vivo result of these modifications is unknown.