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In the diseased fish there was a marked decrease in genes related to amino acid catabolism which could be explained by amino acids being used for increased protein synthesis, however amino acid modification is increased by amino acid transferases and amino acid methylases which may be involved in amino acid biosynthesis.
Furthermore, Nup62, Nup98 and Nup214 are phosphorylated, and O-linked N-acetylglucosamine modification is increased in Nup62 and Nup214 by stress treatment (Crampton et al. 2009).
Consistent with this idea, it was reported that H3K4me3 is enriched across most rDNA repeats, although this modification is increased 5- to 6-fold in sir2Δ cells, primarily at the NTS2 region [ 40].
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The degree of penetration of APPJ surface modification was increased with the increasing pore size.
This modification was increased at −2.5 kb upon CTCF knockdown.
The variance σ of the modification was increased stepwise.
The complexity of ARTD1-dependent histone modifications is increased by the facts that (1) ARTD1 can modify all core histones and the linker histones [ 23], and (2) the size and quality (for example, branching or length) of the polymers may differ under varying conditions and depending on the substrate histone.
As chemical plants are becoming more and more tightly integrated, with extensive material and energy recycling, the need for improving their dynamic properties through process design modifications is increasing.
In addition, analysis of public ChIP-Seq data showed open and active chromatin surrounding the sites of AP4 occupancy at the NOTCH1 promoter, because histone H3K4me1 and H3K27Ac modifications were increased in their vicinity (Supplementary Fig. 9f).
We still detected LRC with low levels of H3diK4 and H3diK9 methylation (Fig. 2M,N), but the proportion of cells with high levels of these modifications was increased compared to wild-type control LRC (Fig. 2M,N).
Nitrosative and oxidative protein modifications are increased in the diaphragm during both MV and experimental sepsis [ 10, 11].
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