Sentence examples for modification is established from inspiring English sources
This epigenetic modification is established and repression is maintained by the action of the polycomb group of proteins (PcG) [27].
Once the initial chromatin modification is established, it can then spread in cis over several kilobases of DNA, irrespective of its sequence.
Like Menin and H3K4me3, this modification was established by hkL treatment alone, suggesting that the NF-κB pathway mediates both H2Bub and H3K4me3 modifications.
The crosstalk between DNA methylation and histone modifications is established by different nuclear factors.
Gurson's model and its numerous modifications are established for simulating ductile failure.
According to the 'classical' view, histone modifications are established in an identical fashion on both copies of each of the four core histones, resulting in 'symmetrically' modified nucleosomes.
Furthermore, we provide important insight on how the plant epigenome changes in response to developmental or environmental stimuli, how chromatin modifications are established and maintained, to which degree they are used throughout the genome, and how chromatin modifications influence each another.
Dramatic allele-specific binding/enrichment of Ctcf, H3K4me3, and H3K9me3 is present at DMR2 in extraembryonic tissues suggesting that these chromatin modifications are established at an earlier stage.
Distinct patterns of DNA methylation and histone modifications are established during cell lineage restriction to determine and maintain cell-type-specific gene expression programs.
To elucidate the regulatory mechanism underlying expression of RS active X-linked genes, we examined how unique profiles of active modifications are established on the X chromosome using the testes of Rnf8 knockout (KO) mice.
Therefore, the timing and dose of drug administration, and IL-2 dose modifications were established on rather empirical assumptions, chiefly based on concerns for safety of the combination and without any specific guidance.
