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Ongoing management of this progressive disease, through medical supervision and diligent lifestyle modification, is critical so that patients can continue to lead active lives.
Since newly cleaved mica is negatively charged at basic pH [4], an advisable surface modification is critical to bind the negatively charged phosphate backbone of DNA.
Small-diameter synthetic vascular grafts have high failure rate due to primarily surface thrombogenicity, and effective surface chemical modification is critical to maintain the patency of the grafts.
Therefore, selecting a proper site for marker modification is critical for successfully constructing the marked viral infectious clone.
Further, MOMP from various chlamydial species is glycosylated (mainly D-mannose-rich) and this modification is critical for MOMP adhesion [ 34- 36].
Our findings indicate that ERK phosphorylates ERG through an interaction with the DEF domain and this modification is critical for ERG to promote prostate cell migration.
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Preservation of desirable chemical, flavor and aroma attributes of the peanut cultivars during the genetic modifications is critical for acceptance of genetically modified peanuts (GMP) by the food industry.
The particle size of nanoclay and its pre-modification are critical to successfully producing a stable complex suspension.
Thus, these structural tRNA modifications are critical for efficient and accurate decoding process and further overall mitochondrial translation (Suzuki and Nagao, 2011).
Both these post-translational modifications are critical for regulating the role of SMARCAD1 in DNA end resection, HR-mediated repair, and cell survival after DNA damage.
Histone modifications are critical in regulating gene expression, cell cycle, cell proliferation, and development.
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