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We also observed four precursor ions containing modification information for lysine 18 and 23.
Note that both models have incorporated the histone modification information.
Mikkelsen et al. [ 28] made the mouse histone modification information available and the human histone modification information was originally from Pan et al. [ 37].
Modification information is captured in PRIDE using the PSI-MOD (Modifications) ontology (13).
Original ChIP-seq data on 8 distinct histone modification information was obtained from [ 26].
The modification detector assigns modification information (i.e. negation and speculation) to each event.
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The elicitation process makes use of the failure data of the past product, the designer information on the effectiveness of planned design/process modifications, information on actual working conditions of the upgraded component and, for outsourced components, technical knowledge on the effect of possible cost reductions.
A second group of proteins that contain modular domains are capable of recognizing or "reading" this phospho-modification information and thereby linking the kinase signal to downstream molecules.
CSI-ANN feeds a linear combination of histone modifications information at a certain window to a time-delay neural network in order to predict enhancers.
Histone modification data were retrieved from human histone modification database (HHMD, http://202.97.205.78/hhmd/index.jsp) [ 32] which contains useful histone modifications information from experimental data that is essential for understanding the modifications at a systematic level (Additional file 2: Table S2).
Third, the interface of PTM proteins is reframed in eight sections to represent the comprehensive annotation of each individual protein and their modification site information, namely protein information, PTMprotein-Annotation, PTMsite-Statistics, PTMsite/Peptide in sequence, PTMsite-Map, Protein/Peptide-Map, PTMsite-Table and PTMsite-Cluster.
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