In addition, sprouting of new connections, dendritic spine growth, and modification in the strength of existing connections are all likely to explain at least part of the observed structural MRI changes [7], [8].
How any such modification could be made without having the aim of introducing "modification in the genome of any descendants" the Council of Europe does not explain.
Comparison to sites of modification in the prokaryotic ribosome suggests how additional modifications enable stabilization of the larger eukaryotic complex.
In conclusion, the connection between RNA modifications, biased codon use, and translational regulation of stress response protein highlights a complicated set of mechanisms to regulate gene expression.
Activity-driven modifications in synaptic connections between neurons in the neocortex may occur during development and learning.
With modifications, it survives to make the connection between energy and rates of change one of the centres of the new science.
That specialization is irreversible in OI organisms considering their genetic isolation from a gene pool for lateral gene transfer has been suggested in other work and is quite reasonable, but it can hardly be construed as a result of this study, and the particular connection to "translation modification" (changes in the apparatus of translation i.e. rRNAs – author's comment) is unsupported.
Depletion of proteins with this specific genetic profile in the absence of Elongator has not been previously described, and demonstrates a connection between codon usage, transcript length, and tRNA modification in determining the expression levels of specific neuronal proteins.
Structural alterations of the adult visual cortex (establishment of new connections through dendritic growth, sprouting, and arborization) seem to be associated with a long duration of visual diseases, following rapid changes associated with modifications in the strength or the unmasking of preexisting connections.
CREB functions as a transcription factor that is expressed in almost all neurons, and has a central role in modification of the strengthening of synaptic connections by regulating several downstream genes in accordance with environmental changes (Carlezon et al, 2005).
Similarly, owing to the connection between ER stress and the mitochondrial regulation of cell death it would be interesting to investigate the modification of lipids present in the MAM in the latter process.
