The development of musical skills by musicians results in specific structural and functional modifications in the brain.
While histone-phosphorylation and histone 1 ADP-ribosylation has been linked to memory training (Chwang et al, 2006; Fontán-Lozano et al, 2010), the best studied histone-modification in the brain next to acetylation is histone-methylation.
This postmortem study was designed to detect developmental and age-associated modifications in the brain of autistic subjects.
Although no direct epigenetic modifications in the brain were examined, the environmentally induced epigenetic transgenerational model used indicates epigenetics can be involved in the induction of the altered behavioral phenotypes.
Our analysis has revealed for the first time evidence of defined modifications in the brain microstructure and neuroconnectivity, in co-occurrence with synaptic efficacy alterations, in a murine model of chronic T. gondii infection.
These findings suggest that structural and functional changes in glaucoma go beyond the visual system, suggesting that POAG can be considered a neurodegenerative vision disease falling within the group of neurodegenerative disorders and, as such, results in widespread modifications of the brain.
Objective: To determine the influence of ammonemia levels and their modification in the variation of brain water contain and the apparition of vasogenic edema.
While a number of NR has been studied, it is unknown whether invalidation of the pregnane xenobiotic receptor (PXR, NR1I2) corresponds to neurological modifications in the adult brain.
After four weeks of everyday meditation, there were noticed functional modifications in the human brain, behavioral changes – cooperation, pro-social behavior, mutual aid -, as well as structural changes.
Although HAR1 is essentially deprived of protein coding genes, it contains the so-called non-coding RNA genes including HAR1F that is expressed in the mammalian neocortex and is now a candidate for being part of a process that brought about innovative structural modifications in the human brain.
To elucidate the cellular pathway and pathogenic role of LRRK2 in PD, we investigated LRRK2 protein modifications and interactors in the brain.
