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Molecular modification in structures of biologically active substances that occur naturally is one of the main strategies to enhance healthy biological effects, as well as to reduce eventual side effects [1 3].
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59 The modifications in structure of the second-generation tetracyclines in comparison with the first-generation tetracyclines improve their gastrointestinal absorption.
Our results further conform to the studies suggesting the proposed value of c-Fos in the modification in structure and function of neurons in mammalian nervous system to help define those brain structures that become activated by stimulation [ 39, 40].
Previous studies indicated that neuronal plasticity results in a cascade of modifications in structures following modification of neural input [ 6– 8].
Finally, gene expression data resulting from microarray hybridizations does not allow exploration of the potential role of protein modification in the structure of multi-subunit complexes.
In addition, the same oclusal alteration performed in the present study showed morphological modifications in other structures of the stomatognatic system [ 22– 22].
The collective behavior of the agents over complex networks largely depends on the structural properties of the networks (Amblard & Deffuant 2004), and minor modification in the structure of the network can have drastic effects on the behavior of opinion formation (Nardini et al. 2008).
Modification in the structure of SAHA altered the specificity of 'δ ' towards a specific HDAC enzyme[83].
Embedding data in an image leads to statistical modification in the structure of cover image.
For Aconite roots, the pharmacodynamic and toxicity level changes occur due to modifications in the structures of Diester Diterpenoid Alkaloids (DDA's) after processing, leading to formation of monoester diterpenoid alkaloids (MDA's) [21 23].
Among recent methods designed for accelerating the EM algorithm without any modification in the structure of EM or in the statistical model, the parabolic acceleration (P-EM) has proved its efficiency.
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