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Instead of analysing the correlation of a single gene with the new biological state (GM, GSEAA derives its power from looking at the effect of genetic modification in sets of genes that share a common biological function, cellular localization, chromosomal location or regulation.
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While previous studies in wheat and barley have revealed the functional role of histone modification in setting VRN1 expression, other mechanisms might also be involved.
Several studies in wheat and barley support a functional role of promoter histone modification in setting VRN1 expression in the triticea [ 25- 27, 70].
The domestication of many seed crops has involved similar modifications in a set of traits including seed dispersal, seed dormancy, gigantism and increased harvest index.
This code might result in distinct combinations SUMO modifications at different sets of lysine residues of Gli proteins with each combination resulting in a different effect on the activity of the Gli protein.
Nag, Savova et al. report that these modifications are found in different sets of genes in different cell types, indicating distinct genome-wide patterns of monoallelic expression.
The results showed high fat and sugar diets of processed food and confectionery were associated with greater modification of IGF2 in both sets of children.
If diphthamide-deficient mutant eEF-2 proteins function perfectly well, it then becomes difficult to understand the retention of the diphthamide modification in such a diverse set of species, which argues strongly for its essentiality.
How any such modification could be made without having the aim of introducing "modification in the genome of any descendants" the Council of Europe does not explain.
It is widely accepted that the installation, maintenance and functional output of epigenetic modifications occur in concert via combinatorial sets of modifications.
The pattern of rRNA modifications and the set of snoRNAs that guide these modifications are conserved in vertebrates.
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