In this work, we used the PCA approach to group the studied ILs based on their structural similarity and to then identify which aspect of the structure is actually responsible for a given IL physicochemical property, as well as how its modification impacts this property.
The degree to which chemical modification impacts RNA quality depends on fixation time (Fig. 3), and also on the RNA isolation procedure.
In this study, we performed gene expression profiling to understand better how PR SUMO modification impacts transcriptional activity and promoter selection.
To begin to investigate how modifications impact allostery in KMD5A, we performed competition-based FP assays to determine affinities of a panel of modified peptides (Fig. 4a).
There is limited information on how these modifications impact the evolved mechanisms of photosynthetic energy metabolism and cellular growth.
It turns out that with the current state of the art, the modifications impact non-technical system attributes.
Yet, it is not known whether the mechanisms that bring about such modifications impact the quantitative or kinetic properties of gene expression.
In recent years, despite the underlying mechanisms of cardiac fibrosis are still unknown, numerous studies suggest that epigenetic modifications impact on the development of cardiac fibrosis.
Particularly, loop-1 modifications impact on the dynamics of a distant region that includes residues from the β-sheet, helix α1 and the C-terminal.
