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However, analyzing the data afterwards is difficult because part of the modification history disappears during the process.
Similar observations on the CP814E morphology have been reported in the literature with the nano-sized crystals having different sizes depending on the synthesis or modification history [29, 30].
In history based parametric CAD modeling systems, persistent identification of the topological entities after design modification is mandatory to keep the design intent by recording model creation history and modification history.
To account for the changed data structure, the derived model history functionality was extended to include the modification history of the parent model.
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There is clearly a duality in Darwin's theory of descent with modification; the history of variation is well described by a network and the history of selection is well described by a tree.
Author's response: See our reply to Eric Bapteste I disagree with the allusions to Darwin in the discussion section " There is clearly a duality in Darwin's theory of descent with modification; the history of variation is well described by a network and the history of selection is well described by a tree".
With regard to all-cause mortality, we found significant effect modification by history of hypertension (P interaction=0.02) suggesting increased risk of death from any cause for women with a history of hypertension (hazard ratio 1.31 (0.92 to 1.86)).
There was also no effect modification by history of prior MI (P for interaction term = 0.41).
In secondary analyses, we found no evidence of significant effect modification by history of hypertension, baseline score, perceived change in memory, or educational attainment.
Contributions of vitamin D intake to risk for breast cancer and bone mineral density, as well as potential effect modification by history of smoking, should be further studied to elucidate the precise biologic mechanisms.
In addition, there were no significant effect modifications between history of previous malignancy and other risk factors in terms of their effect on lung cancer risk.
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