Sentence examples for modification for regulating from inspiring English sources

Phosphorylation/Dephosphorylation is the most common post-translational modification for regulating protein function.

We would like to point out that besides phosphorylation, a dominant post-translational modification for regulating protein stability and activity, other types of modification such as ubiquitination, methylation and glycosilation have also been shown to be involved in tuning the stability, activity and translocation of macromolecules.

Therefore, acetylation is another candidate modification for regulating tau turnover indirectly through the ubiquitin proteasome system [ 46].

These data indicate that K254 methylation must occur at the expense of ubiquitylation, and thus is a candidate modification for regulating protein degradation via the ubiquitin proteasome system [ 46].

Protein glutathionylation (reversible formation of GS S-protein GS S-proteinis also an important post-translational modisulfides for regulatisg protein function alsoprotecting exposed cysteine (Cys) residues from irreversible danage durimportanttive stress.

(113) Philip Bevilacqua's group (Pennsylvania State University) is developing mRNA-based therapeutics by designing nucleoside modifications for regulating the activity of PKR.

DNA methylation is a major epigenetic modification important for regulating gene expression and suppressing spurious transcription.

Epigenetic mechanisms are stable and heritable modifications responsible for regulating gene transcription without altering the DNA's nucleotide sequence [ 1].

Posttranslational modification is critical for regulating the localization, stability, and activity of proteins, as well as their ability to form macromolecular complexes (Walsh 2006).

It has been shown that both the histone tails and globular domains are subjected to a diverse array of the posttranslational covalent modifications (e.g. acetylation and methylation), and that such modifications are pivotal for regulating chromatin dynamics and transcriptional output of the gene/genome (1 4).

Both these post-translational modifications are critical for regulating the role of SMARCAD1 in DNA end resection, HR-mediated repair, and cell survival after DNA damage.