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Table 1 shows a comparison of the reaction conditions between the original method and the modification for our HT assay.
While potentially applicable to all sequencing platforms, we developed SuBLiME technology using SOLiD sequencing, as linker sequences were readily amenable to necessary modification for our protocol (Table S1 ).
Although the methods were designed for a different type of biomedical relation, they did not require any modification for our application.
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Thus, the model needs modifications for our case since we are using a different catalyst.
The obtained theoretical studies are in agreement with the in vitro bioassay screening results, which supports the importance of the structural modifications for our studied compounds.
In addition, although we already considered some peptide modifications for our database searches, such as carbamidation of cysteines or oxidation of methionines, other types of modifications can occur and impair database searches and protein identifications.
There is no need for special modification of our method for actual robots, and we have already applied it to simple pushing tasks by an industrial manipulator successfully [20,22].
Molecular modeling also provides a rational basis for modification of our three lead compounds to identify related ones with greater potency; these studies are underway.
There are many possible solutions for modification of our algorithm to handle these retinal pathologies.
Saturated and unsaturated fatty acids with carbon numbers of 13, 15, and 17 were subjects for modification of our model.
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CEO of Professional Science Editing for Scientists @ prosciediting.com