Exact(2)
Thus, proteins that require such modification for biologic activity should be studied in their myristoylated form.
Full-length adiponectin (fAd) requires posttranslational modification for biologic activity (e.g., hydroxylation and glycosylation) and is secreted from adipocytes in three major size classes: trimers (∼90 kDa; the basic unit), low-molecular-weight (LMW) hexamers (∼180 kDa), and high-molecular-weight (HMW) isoforms consisting of 12-mers to 18-mers (which can exceed 400 kDa) [ 26, 27].
Similar(57)
We further evaluated any observed effect measure modification for evidence of biologic interaction using standard measures (Supplementary materials).
These cytokines seem to induce signals in a manner similar to IL-1, but at much higher concentrations (100- to 1,000-fold 1,000-foldng that the recombinant IL-1F proteinsuggestingall previous sthates lack postherecombinantl modifications that might be improteinsfor biologic activities of the endogenousedroteins.
But surviving in pounding surf is difficult, and sand is generally not a good medium for biologic preservation.
For example, there is research looking for biologic targets in order to develop the next drug.
Effect measure modification and biologic interaction were also extensively evaluated.
Such agents are called "biologics," an abbreviated colloquial term for "biologic response modifiers" (Köller 2006).
But major variability can occur even for biologic questions.
Apart from RF for biologic DMARD-treated patients, no significant differences were seen between patients treated with biologics and those taking non-biologics.
A nonfasting blood sample was collected for biologic measurements.
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