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MPs expressed on the cell surface maintain their native features: folding, post-translation modification, expression of splicing variants and formation of multimeric complexes.
Among the three proteins associated with chromatin modification, expression of Huwe1and Nasp decreased in WT cells.
5, 45– 48 According to this observation, the elevated expression of miRNAs in tumors and adjacent tissues should be linked to DNA methylation patterns in cancer (possibly with histone modification, expression of small RNAs, etc).
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These results thus indicate that the genetic modification did not result in unintended qualitative and/or quantitative modification of expression of intrinsic allergens.
Although the epigenetic modification on parental genes should be complementary within a species, it is possible that the pattern of epigenetic modification and expression of imprinted genes are different in distant species [ 37].
To validate the hormonal modulation leading the root phenotypic modification, the expression of auxin-responsive genes (AUX/IAA) of rice were assessed by reverse transcriptase quantitative PCR.
Pathway splitting and coculture could be combined with an increase in gene dosage and modification and expression of a statin pump protein in the future, and this strategy may further improve lovastatin production.
Epistasis, the modification of expression of one gene by one or several other genes, is believed to be an important genetic contributor to complex diseases, including pre-eclampsia.
In this study, the local importance measure was exploited to predict microRNAs (miRNAs) that are significantly associated to the modification of expression of specific mRNAs [ 76].
R. africae, however, has more spoT genes than R. conorii or R. rickettsii and does not show any modification of expression of its specific spoT15 gene during temperature variations.
This rapid elongation of the posterior forelimb digits is thought to results from modification in expression of key developmental genes [ 5, 6].
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