Sentence examples for modification essential for from inspiring English sources

Prenylation is a posttranslational modification essential for the proper localization and function of many proteins.

DNA methylation is a well-studied epigenetic modification essential for efficient cellular differentiation.

IR induces SMARCAD1 phosphorylation at a conserved T906 by ATM kinase, a modification essential for SMARCAD1 recruitment to DSBs.

Herein, we demonstrate that Br− is a required cofactor for peroxidasin-catalyzed formation of sulfilimine crosslinks, a posttranslational modification essential for tissue development and architecture found within the collagen IV scaffold of basement membranes (BMs).

The PKA catalytic subunit PKAcα binds and phosphorylates HSF1 on serine 320, a modification essential for nuclear localization, association with the hsp70.1 promoter and transcription.

The trimethylation of H3K27 is a repressive histone modification essential for gene silencing by PcGs and it has been suggested that this epigenetic mark functions to recruit PRC1 to chromatin [22].

Since identification of proteins arginylated in vivo is only at its initial stages, it is also possible that some of the arginylated proteins, or proteins regulated by arginyltransferase, have additional roles in germ cell development, for example in regulating the epigenetic modifications essential for normal gametogenesis.

Thus, the human genome sequence contains signatures for chromatin modifications essential for gene regulation and development.

Histone modifications essential for activation of chromatin domains have been discussed in terms of transitions between 30-nm and 10-nm chromatin fibers.

Fibrillarin functions in snoRNP complexes to effect rRNA modifications essential for rRNA folding and stability during their biogenesis and the presence of which indicates nucleolar activity [ 26].

Furthermore, this modification is essential for ghrelin's activity.