The function of the DMC is to monitor the course of the study and if necessary to give a recommendation to the study administration for discontinuation, modification or continuation of the study.
The steering committee supervises the conduct of the trial and issues recommendations for early termination, modifications or continuation of the trial, if necessary.
The advisory board supervises the conduct of the study and issues recommendations for early termination, modifications or continuation of the study, if necessary.
Advisory board An independent scientific advisory board was established to supervise the conduct of the trial and to issue recommendations for early termination, modifications or continuation of the trial, if necessary.
The proof of the main result (cf. Theorem 3.1 below) will be based on the following slight modification of the continuation principle developed in [19].
Make recommendations to HREC concerning the continuation, modification or termination of the trial.
64 The DSMB will comprise independent, multidisciplinary experts who will make recommendations regarding the continuation, modification or termination of the trial.
Subsequently, the Data Safety and Monitoring Committee makes recommendations to the Steering Committee (and occasionally other government regulatory organisations) regarding the continuation, modification, or cessation of the clinical trial.
The DMC and TSC will monitor progress of the trial, adverse event data and will recommend continuation, modification or early termination of the trial.
